SIAT Research
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Apr 24, 2025Oscillating Microbubble Array-based Metamaterials (OMAMs) for Rapid Isolation of High-Purity ExosomesCompared to existing methods, the OMAMs platform offers a significantly faster, simpler, and potentially more cost-effective route to obtaining high-purity exosomes directly from clinical samples. ... Exosomes, secreted by most cells, carry biological information and proteins that serve as noninvasive biomarkers for diagnosing and predicting disease progression and metastasis. However, the rapid... -
Apr 17, 2025Living Hydrogel-based Miniaturized and Portable Bio-battery for Precise Nerve StimulationResearchers develop a miniaturized, portable bio-battery measuring 20 millimeters in diameter and 3.2 millimeters in height. This innovative device integrates a bioelectric stimulation mechanism, e... A research team led by ZHONG Chao, LIU Zhiyuan, and WANG Xinyu from the Shenzhen Institutes of Advanced Technology (SIAT) of Chinese Academy of Sciences, in collaboration with WANG Renheng from She... -
Apr 14, 2025Head-Mounted Microscope Reveals High-Resolution Neurovascular Dynamics in Freely Behaving MiceThe microscope, for the first time, enables dual-modal imaging at high spatiotemporal resolution, enhancing our understanding of neurovascular coupling mechanisms without affecting the natural beha... A research team led by Prof. LIU Chengbo from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences, has developed a groundbreaking 1.7-gram head-mounted microsco... -
Apr 08, 2025Newly Discovered PNS Microglia Found to Regulate Neuron SizeThe key finding of the study is that PNS microglia share a common molecular signature, protein marker, epigenetic profile, and ontogenetic trajectory with the CNS microglia in humans. This finding ... In a study published in Cell on April 7, a research team led by Prof. LI Hanjie from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences has revealed the presen... -
Mar 04, 2025Researchers Reveal Key Mechanism Behind Bacterial Cancer TherapyThe findings illuminate a crucial, yet previously unresolved mechanism in bacterial cancer therapy. A research team led by Prof. LIU Chenli from the Shenzhen Institutes of Advanced Technology of the Chinese Academy of Sciences (CAS) and Prof. XIAO Yichuan from the Shanghai Institute of Nutrition ... -
Jan 23, 2025Researchers Develop Novel Proteolysis-targeting (PROTAR) Live Attenuated Vaccine StrategiesThese studies provide new approaches for developing safe and effective live attenuated vaccines. Recently, Prof. SI Longlong's team from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences, published two studies in Nature Microbiology and Nature Chemical Bi... -
Jan 16, 2025Researchers Reveal Novel Mechanisms of the Neurodirecting Factor Sema3A Protects CartilageThis research may provide a novel biological therapeutic option to arrest chondrocyte degeneration. Osteoarthritis (OA), is a common degenerative joint disease that affects millions of people worldwide, particularly targets the knee joint. Over time, the cartilage within the joint wears down, lea... -
Jan 13, 2025How Can We Measure How Much We Eat?Scientists derived a predictive model/equation by combining classical statistics and machine learning for total energy expenditure. Recently, an international team led by Prof. John Speakman from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences, alongside the International Atomic Energy A...