SIAT Research
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Nov 20, 2025New Intraoperative SERS Navigation System Enables Real-Time Malignancy Grading of Prostate TumorsResearch team has developed a label-free intraoperative navigation system based on surface-enhanced Raman scattering (SERS) that enables real-time, in situ grading of prostate tumor malignancy by s... Precise identification of tumor boundaries during radical prostatectomy remains a major clinical challenge, with positive surgical margins occurring in 15–40% of prostate cancer cases, significant... -
Nov 20, 2025Scientists Reveals "Source-Sink" Mechanisms and Ecological Drivers of Carbon Sequestration in the Greater Bay AreaA "scientific diagnosis report" on the estuarine carbon cycle. The coastal ecosystems of the Guangdong-Hong Kong-Macao Greater Bay Area (GBA) faces pressure from high-intensity anthropogenic activities, making the high-resolution scientific assessment of its c... -
Nov 17, 2025Target binding of black phosphorus nanomaterial to polo-like kinase 1 for cancer chemotherapy: a mutual selection of nanomaterial and proteinThis work uncovered how black phosphorus nanomaterials (BPNMs) recognize and bind a key cell cycle regulator, polo like kinase 1 (PLK1). Understanding how nanomaterials interact with biological macromolecules is essential for advancing nanomedicine. Over the past two decades, the "protein corona" concept has guided research into nan... -
Nov 17, 2025Whole-Body PET/CT Study Maps Inter-Organ Metabolic Networks Across the Glycemic SpectrumThis research uncovered how metabolic coordination among major organs shifts across normal glycemia, prediabetes, and diabetes. Diabetes is now understood to be a systemic metabolic disorder, involving disruptions across multiple organs rather than a single glycemic pathway. Yet, in clinical practice, metabolic health is st... -
Nov 12, 2025Researchers Uncover the Mechanism of Plasma Membrane Remodeling that Drives Mitotic Cell RoundingResearchers uncovered a fundamental plasma membrane remodeling mechanism that governs the mitotic cell rounding. During cell division, adherent animal cells round up to create the precise spatial geometry required for accurate chromosome segregation, a process that depends on the coordinated remodeling of the... -
Nov 04, 2025New Cell-scale Method Reconstructs Whole-brain Fiber Tracts from Routine HistologyThis work published in Nature Methods, offers a practical route to high-precision, high-throughput connectome mapping with potential applications in psychiatry and epilepsy. In a study published in Nature Methods on November 3, researchers from Shenzhen Institute of Advanced Technology of the Chinese Academy of Sciences (CAS) and the Center for Excellence in Brain Scie... -
Oct 23, 2025Researchers Reveal Mystery of Neurotransmission with Time-resolved Cryo-ETThis study offers a fresh perspective on neurotransmission, synaptic plasticity, and related brain functions and diseases. In a study published in Science on October 17, a team led by Prof. BI Guoqiang from the University of Science and Technology of China/Shenzhen Institutes of Advanced Technology of the Chinese Acad... -
Oct 21, 2025Universal In-Situ Cross-Linking Strategy Enhances Stability of Inverted Perovskite Solar CellsThis work provides a practical strategy to improve the stability of efficient SAM-based devices on rough substrates, advancing the commercialization of inverted perovskite and tandem solar cells. Hole-selective self-assembled monolayers (SAMs) are ultrathin organic films that play a crucial role in modern optoelectronic devices, particularly in perovskite and silicon-perovskite tandem solar...