SIAT Research
-
Jan 10, 2023Genetically Engineered Bacterium Enables Biosynthesis of Melanin Nanoparticles"This study provides a rationale for the biomedical applications of biosynthetic melanin nanoparticles," said Prof. YAN Fei, "and encourages other researchers to produce nanomaterials by microorgan... Photothermal therapy (PTT) has attracted considerable attention for tumor treatment due to its unique advantages in minimal invasiveness and spatiotemporal selectivity.Melanin is a kind of multifun... -
Dec 26, 2022Mapping the Neural Circuitry of Predator Fear in the Nonhuman PrimateThis work was awarded 'Editors' Choice', an award given by the Nature-Springer Group and the journal Brain Structure and Function during the Cajal Club at the Society for Neuroscience conference 2023. The innate fear networks are becoming better known in rodents, with major discoveries having been made in the last decade. But to really exploit them, we need to compare these networks between rode... -
Dec 26, 2022Successful Hypothermia in Nonhuman Primate Paves the Way for Future Application in Human TorporThe team has recently reported the first reliable hypothermia in nonhuman primates caused by activating a group of hypothalamic neurons. Hibernation is a state adopted by certain mammals as an adaptation to adverse winter conditions. Typical features of hibernation include greatly reduced metabolic activity and lowered body temperat... -
Dec 07, 2022New Strategy Enables Targeted Degradation of Extracellular and Membrane-associated ProteinsAs demonstrated in the development of BMS-L1-RGD, which is an efficient programmed death-ligand 1 (PD-L1) degrader validated both in vitro and in vivo, the IFLD strategy expands the toolbox for reg... Targeted protein degradation (TPD) technologies including the traditional proteolysis targeting chimeras (PROTACs), the recently reported lysosome-targeting chimeras (LYTACs) and related technologi... -
Dec 06, 2022Phase Separation of Scaffold Protein Regulates Microbial Asymmetric Cell DivisionThe team proposed that the PodJ scaffold in the new cell pole forms biomolecular condensates with physiological functions via phase separation, which helps to establish and regulate the asymmetry o... By polarizing different cell fate determinants at opposite cell poles, asymmetric cell division (ACD) that produces distinct daughter cells is an evolutionarily conserved mechanism to generate cell... -
Nov 25, 2022How Much Water Do We Need a Day?"The main outcome of our study was a general equation for predicting water turnover. This will help countries anticipate their future water needs," said Prof. Speakman. A new study led by Prof. John Speakman from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences (CAS) and the University of Aberdeen shows that the recommended w... -
Nov 14, 2022Hybridization of Surface Lattice Resonances Induces Dual-Band Bound States in the ContinuumThe researchers expected that this concept will help to suppress the inherent losses and to achieve high Q-factors for plasmonic metasurfaces, on which they finished the experimental demonstration ... High quality factors (Q-factors) are favorable in a diverse range of applications, ranging from photoluminance, lasers, nonlinear optics, strong coupling, and optical sensing. In metasurfaces, surf... -
Nov 14, 2022Researchers Reveal How Nucleus Accumbens Mediates Positive and Negative Motivational ValenceReward-seeking and threat avoidance are critical for survival. Pursuing enjoyable things triggers the release of dopamine in the brain, making people feel pleasure. On the contrary, people subconsc...