SIAT Research
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Aug 11, 2025Novel Biological Signal-Processing Framework Precisely Decodes Complex Cellular LanguageThis study introduces a framework that integrates orthogonal operational amplifiers into standardized biological processes to enable efficient signal decomposition and amplification. Cells naturally process external signals through intricate genetic circuits, enabling adaptation to diverse environments. These circuits rely on complex, nonlinear interactions among genes and prot... -
Aug 07, 2025First Evidence that Lifelong Oral Nicotine Shapes Motor and Metabolic Aging in MiceThis study offers a mechanistic framework for evaluating long‑term nicotine exposure and inspire the future development of "non‑addictive cholinergic metabolic modulators". As global populations age, preserving mobility and metabolic resilience has become a central challenge for healthy aging. Aging is a systemic process marked by energy imbalance and organ‑specific ... -
Jul 29, 2025Researchers Develop Bacterial Cellulose-Based Dressing for Advanced Burn Wound CareThis study develops a thrombin-anchored bacterial cellulose (T-BC) dressing for advanced burn care, enabling rapid and sustained hemostasis while preserving the structural and hydration benefits of... Recently, a research team led by Dr. ZHONG Chao and Dr. AN Bolin from the Shenzhen Institutes of Advanced Technology of the Chinese Academy of Sciences, collaborating with Dr. LIU Yan from Ruijin H... -
Jul 22, 2025Researchers Develop New Microscope for Neurovascular Coupling ImagingThe study presents a linear transducer array–based hybrid microscope that integrates photoacoustic microscopy and confocal fluorescence microscopy to enable simultaneous neurovascular imaging. The... Neurovascular coupling (NVC) is the dynamic regulation of cerebral blood flow in response to neural activity. Specifically, when neurons become active, nearby blood vessels dilate to increase blood... -
Jul 18, 2025Researchers Develop Microlens-Augmented AFM for Real-Time Nanoscale Observation and Control
This paper presents a nanomanipulation approach enabled by real-time super-resolution imaging guidance. Atomic force microscopy (AFM) is a cornerstone technique for nanoscale manipulation, enabling critical applications in nanoparticle assembly, biomolecule handling, semiconductor device manufacturin... -
Jul 08, 2025Deep Learning-based Model Enables Fast and Accurate Stroke Risk PredictionIn this study, an automated method for lumen, vessel wall, and plaque segmentation for quantitative assessment based on MR vessel wall images and a CNN model with different priors was developed and... Stroke is the second leading cause of death globally. Ischemic stroke, strongly linked to atherosclerotic plaques, requires accurate plaque and vessel wall segmentation and quantification for defin... -
Jun 30, 2025Researchers Uncover Novel Mechanism for Regulating Ribosome Biogenesis During Brain DevelopmentThis study expands the understanding of the complex regulatory networks that govern protein synthesis and underscores the critical role of mRNA modifications in fine-tuning essential cellular proce... Ribosomes are tiny molecular machines inside all living cells that build proteins, and ribosome biogenesis is the complex, multi-step process by which they are made.During brain development, neural... -
Jun 25, 2025Regular Opioid Use May Increase Dementia RiskA 20% increased risk of all-cause dementia was observed among individuals with regular opioid use compared to non-users. Chronic non-cancer pain (CNCP) is defined as any painful condition that persists for more than three months and is unrelated to malignancy, affecting around 30% of people worldwide. Opioid use for ...