SIAT Research
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Jan 18, 2021Living Macrophage Drug Promotes Antitumor ImmunotherapyA research team led by Prof. CAI Lintao at the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences developed a "cytopharmaceutical" based on living macrophages. Immunotherapy is one of the most promising approaches to inhibit tumor growth and metastasis by activating host immune functions. However, so far, immunotherapy still exhibits limitations of effica... -
Jan 15, 2021Researchers Reveal Novel Function of Ciliopathy Protein CEP290 in the Initiation of CiliogenesisDr. WEI Qing’s group from Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences reported that ciliopathy protein CEP290 was essential for the initiation of ciliary TZ... Cilia are ubiquitous in human tissues, and the dysfunction of cilia can cause many organ defects and lead to over 35 kinds of human genetic diseases, collectively termed as ciliopathy.The transitio... -
Jan 07, 2021Researchers Develop New Method to Revamp and Minimize Yeast Genomeshowed that a synthetic chromosome arm (synXIIL) could be efficiently reduced, their study was published in Genome Biology on Jan 4. Researchers from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences developed a method termed SCRaMbLE-based genome compaction (SGC) to revamp and minimize the... -
Jan 06, 2021Deep Learning Helps Predicting Occult Peritoneal Metastasis in Stomach CancerA new study published in the JAMA Network Open on Jan. 5 shows that deep learning can help predicting the occult peritoneal metastasis in stomach cancer. It provides a novel and noninvasive approac... Stomach cancer, or gastric cancer, is a common gastrointestinal malignancy. Peritoneal metastasis occurs in a majority of patients with advanced stomach cancer and is considered as an aggressive di... -
Dec 18, 2020Researchers Reveal Seasonal Plasticity in the Mammalian BrainResearchers from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences (CAS), in collaboration with colleagues from Germany and Israel have now studied the season... The brain is remarkable for its plasticity, the ability to change and adapt to environmental, behavioral, and metabolic conditions. However, the most studied forms of plasticity occur at very short... -
Dec 07, 2020Researchers Reveal Clinical Histone Deacetylase Inhibitors are Effective Drugs against COVID-19A team led by Prof. YUAN Shuguang from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences has found that several histone deacetylase (HDAC) inhibitors could bi... The Corona Virus Disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has posed serious health threats to humanity and jeopardized the global economy.H... -
Nov 18, 2020Magnetic Spray: Giving Inanimate Objects New BionergyResearchers from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences, together with the City University of Hong Kong (CityU), have developed an agglutinate, rep... Millirobots that can adapt to unstructured environments, operate in confined spaces, and interact with a diverse range of objects would be desirable for exploration and biomedical applications. How... -
Oct 26, 2020Scientists Quantify Dramatic Uneven Urbanization of Large Cities throughout the World in Recent DecadesScientists addressed the following questions: (i) How have global large cities developed in recent decades in terms of urban expansion, population growth, and urban greenness change? (ii) What are ... According to the latest report from the United Nations (UN), the global population will reach 9.7 billion, and 68% of the population will live in urban areas in 2050. Undoubtedly, urban sustainable...