SIAT Research
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Apr 26, 2024Bioorthogonal/Ultrasound Activated Oncolytic Pyroptosis for Augmented In Situ Tumor VaccinationThis work provides a novel strategy to pursue oncolytic pyroptosis and convert tumor into in situ vaccine factory for boosted antitumor immunity. The development of personalized tumor vaccines has shown great promise in the field of cancer immunotherapy. However, the effectiveness of in situ tumor vaccines, which are derived from immunogenic... -
Apr 17, 2024Researchers Unveil Vital Role of Astrocytes in Mental Health"This study furnishes fresh evidence regarding the critical role of astrocytes in regulating behavior and presents novel therapeutic targets for addressing impairments in risk assessment function w... Astrocytes as vital cells in the central nervous system are crucial for brain health and function. Recent research indicates that they influence higher cognitive functions and behaviors by regulati... -
Mar 29, 2024Novel Method by Chinese Scientists Revolutionizes Bacterial Viability DetectionThis work exemplified the power of interdisciplinary collaboration in driving scientific breakthroughs and provided a valuable framework for future research in the fields of microbiology, nanotechn... Recently, Prof. GUO Shifeng’s team at the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences, proposed a novel method that fills the gap between physical measureme... -
Mar 13, 2024Researchers Unveil low-Energy Synthesis of Bulk van der Waals MaterialsResearchers from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences, in collaboration with partners from the Shenzhen International Graduate School of Tsinghua ... -
Mar 11, 2024Scientists Develop Efficient Method for Reshaping Yeast DNAThis work sheds light on the high plasticity of rDNA organization and paves the way for the future rDNA engineering. Chinese scientists, along with their international counterparts from the University of Manchester, have developed a method called construction of a repetitive array by transformation (CAT) for effi... -
Mar 06, 2024Researchers Develop High-Performance MXene/Polydopamine Bioelectrodes, Paving the Way for Cost-Effective Bioelectronics"Our bioelectrodes demonstrate a remarkable reduction in cost," said Prof. ZHANG Yi, "It holds great promise for the utilization of new-generation bioelectronic interfaces in both research and clin... The ideal bioelectronic interfaces typically necessitate bioelectrodes that fulfill practical requirements, including low interface impedance, exceptional long-term stability, and biosafety.However... -
Mar 05, 2024Unlocking Cellular Mysteries: Advancements in Single-Cell Omics Analysis with Genome-Scale Metabolic ModelingWhile GEMs are mainly used to analyze single-cell RNAseq data, with the development of single-cell proteomics and metabolomics, it is believed that GEM-aided analysis of multi-omics of single cells... The widespread applications of single-cell technologies have generated a large amount of single-cell data, resulting in a growing need for methods for single-cell data analysis and interpretation. ... -
Mar 05, 2024Researchers Develop Dynamic Model Integrating Protein Allocation with Flux Balance AnalysisThis work provides a quantitative tool to investigate cellular metabolism under varying environments and reveals insights into bacterial adaptation strategies. Recently, a research team led by Prof. FU Xiongfei from the Shenzhen Institute of Advanced Technology of Chinese Academy of Sciences has developed a dynamic model integrating protein allocation wit...