SIAT Research
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Dec 22, 2025Premating Maternal Stress Induces Sex-Specific Emotional ChangesThe study uncovered how psychological stress experienced by mothers before conception may shape the long-term emotional behaviors of their offspring and revealed a previously unrecognized brain–bo... Women experience mood disorders at disproportionately high rates, and maternal emotional disturbances around pregnancy are known to increase children's vulnerability to neurodevelopmental and psych... -
Dec 11, 2025Scientists Develop Novel "Super-sensitive, Low-burden" Mammalian Cell-cell Communication SystemThe study revealed the small-molecule signaling system for mammalian cell-cell communication that combines super-sensitivity with a chassis-friendly, low-burden design, and demonstrated the system'... Cell-cell communication, as the "conductor" of physiological activities, transmits information through signaling molecules, coordinating development, immunity, and homeostasis. During embryonic con... -
Dec 05, 2025Global 10m Resolution PV Power Plant Dataset (2019-2025): A Breakthrough via ANDPI and Multi-Source Data FusionThe study developed a 10-meter resolution global dataset of centralized photovoltaic (PV) power plants. As one of the most promising renewable energy technologies worldwide, photovoltaic (PV) power plays a pivotal role in achieving carbon neutrality, and accurately locating PV power plants and tracki... -
Dec 03, 2025CEST-MRI Study Develops Joint Motion–Intensity Correction Framework for Enhanced Quantitative ImagingThe study developed the motion–intensity joint correction framework specifically tailored to CEST-MRI. Chemical Exchange Saturation Transfer (CEST) MRI is a molecular imaging approach that can sensitively probe tissue metabolism and microenvironment through frequency-selective saturation and exchang... -
Dec 02, 2025Bacteroides fragilis Activates a Cholinergic Gut–Brain Circuit to Suppress SeizuresThe study reveals how Bacteroides fragilis activates a previously unrecognized cholinergic gut–vagus–brain circuit and demonstrates its therapeutic potential in both animal models and children wi... In a study published in Neuron on January 16, a research team led by Prof. LIU Xin'an and Prof. CHEN Zuxin from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Scienc... -
Nov 28, 2025Exploring Functional Insights into the Human Gut Microbiome via the Structural ProteomeThis study established a structural proteome database and structure-based retrieval framework for the human gut microbiome, significantly improving the ability to predict functional "dark matter" s... Despite rapid advances in microbiome research, a large proportion of proteins encoded by the human gut microbiome remain functionally uncharacterized. Sequence-based methods often fail to annotate ... -
Nov 20, 2025New Intraoperative SERS Navigation System Enables Real-Time Malignancy Grading of Prostate TumorsResearch team has developed a label-free intraoperative navigation system based on surface-enhanced Raman scattering (SERS) that enables real-time, in situ grading of prostate tumor malignancy by s... Precise identification of tumor boundaries during radical prostatectomy remains a major clinical challenge, with positive surgical margins occurring in 15–40% of prostate cancer cases, significant... -
Nov 20, 2025Scientists Reveals "Source-Sink" Mechanisms and Ecological Drivers of Carbon Sequestration in the Greater Bay AreaA "scientific diagnosis report" on the estuarine carbon cycle. The coastal ecosystems of the Guangdong-Hong Kong-Macao Greater Bay Area (GBA) faces pressure from high-intensity anthropogenic activities, making the high-resolution scientific assessment of its c...