SIAT Research
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Oct 23, 2024Researchers Reveal Novel Therapeutic Approach for Rheumatoid ArthritisThis work not only identifies a potential valuable biomarker for monitoring the progression of RA but also offers a promising approach for its effective treatment. Rheumatoid arthritis (RA) is the most common form of chronic inflammatory arthritis, characterized by synovitis and progressive destruction of bone and cartilage in the affected joints. Conventiona... -
Sep 30, 2024Researchers Develop Vision-Language Foundation Model for Enhancing Medical DiagnosticsResearchers develop chest X-ray vision-language foundation model, MaCo, reducing the dependency on annotations while improving both clinical efficiency and diagnostic accuracy. A research team led by Prof. WANG Shanshan at the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences, together with collaborators, has developed a chest X-ray visio... -
Sep 25, 2024Novel Model for Identifying Focal Cortical Dysplasia Lesion from MR images“As far as we know, this is the first study to apply a transformer-based model for the FCD lesion segmentation”, said Dr. XU, “our study promises to be a valuable tool for medical practitioners,... Epilepsy is a neurological condition marked by epileptic seizures. Focal cortical dysplasia (FCD) is a leading cause of drug-resistant epilepsy. Surgical removal of FCD lesions is the most effectiv... -
Sep 13, 2024Researchers Reveal Competition-integration Mechanism of Space-time Encoding in Hippocampal NeuronsIn this study, researchers reported a competition-integration mechanism of space-time encoding in individual hippocampal neurons, providing an essential neural basis for understanding episodic memo... Recently, a collaborative research team led by Prof. WANG Cheng from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences, and assistant Prof. CHEN Xiaojing from ... -
Sep 06, 2024Researchers Predict Colonization Outcomes of Complex Microbial Communities by Machine-learning ModelsIn this study, the researchers systematically evaluated the proposed data-driven approach by employing synthetic data generated from classical ecological dynamical models and in vitro human stool-d... Microbial communities are constantly exposed to the invasion of exogenous species, which can significantly modify their composition and function. The capacity of a microbial community to resist inv... -
Sep 04, 2024Researchers Reveal New Central Action Target of the “Weight Loss Miracle Drug” GLP-1R Agonists in MiceResearchers revealed the essential role of lateral septum (LS) neurons in mediating anorectic and weight-lowering effects of the anti-obesity drug— liraglutide in mice. A research group led by Prof. ZHU Yingjie from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences (CAS), has revealed the essential role of lateral septum (LS) ... -
Sep 03, 2024Researchers Develop Novel Post-bioprinting Strategy for Reconstruction of Challenging Bone DefectsThe researchers developed a type of heart-inspired hollow hydrogel-based scaffold (HHS) that can reversibly respond to external mechanical stimulations are used for active cell loading in a rapid, ... A research team led by Prof. RUAN Changshun from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences has proposed a mechanical-assisted post-bioprinting strategy... -
Aug 29, 2024Researchers Reveal New Role of Cohesin Complex in Controlling Gene CoexpressionResearchers discovered an unknown role of cohesin complex in controlling gene expression, thereby resolving the long-standing puzzle regarding the general function of genome structure in gene regul... In a study published in Nature Genetics on July 24, scientists from the Shenzhen Institute of Advanced Technology Chinese Academy of Sciences and the Howard Hughes Medical Institute/Janelia Researc...